孕期影响胎儿的职业与嗜好权衡

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职业性因素。职业性因素对妇女生殖能力、，对男性生殖机能及第二代健康的影响均不能忽视。从到胚层形成这一时期，对有害因素较不敏感，受精后第18天至第60天是敏感期，此后随的增加，敏感性逐降。除对胚胎的作用外，职业性有害因素可促进妊娠及期并发症增加，从而影响胎婴儿质量。

常见职业性有害因素如铅、汞扁、砷、汽油、二硫化碳、三氯乙烯、氯乙烯、氯丁二烯、剂气体、放射线、噪音、微波等，经动物实验证明对胚胎及胎儿有害的职业性化学物质已不下数百种，至于对人类胎儿的影响必须在此基础上进一步研究。

嗜好问题。吸烟吸烟孕妇的新生儿，比正常儿体重减少g，且率高。Wilson（1973）观察吸烟孕妇组所生婴儿先天性心脏病占7.3‰，对照非吸烟组为4.7‰。Hernberg(1982)报告父亲吸烟，母亲不吸烟者，子代的先天缺陷发生率及围产期死亡率，均随父亲吸烟支数加多而升高。父亲不吸烟者，子代先天缺陷率为0.8%；父亲每天吸烟支时则为1.4%；每天吸烟＞10支时为2.1%。酒精慢性酒精中毒孕妇所生婴儿有酒精综合征的先天性异常表现，已成为西方世界的社会问题。患儿小头、小眼球、小下颚、房间隔缺损、外阴畸形及四肢运动障碍。

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